5% Closan Inj. Closantel
Author:admin

Composition:
Contains per ml:
Closantel (as Sodium)...........50 mg.
Excipients ad ..........................1 ml.


Indications:
Closantel is a synthetic anti parasitic agent which is highly effective against liver fluke,blood sucking nematodes and larval stages of some arthropods in sheep and cattle.
Closantel decouples the mitochondrial oxidative phosphorylation, which leads to the inhibition of ATP synthesis. That causes a significant change in the energy
metabolism, and as a consequence the death of the
parasite.


Contra-indications:
Hypersensitivity to closantel.
Do not use for intravenous or intramuscular administration.
Do not use in cattle or ewes producing milk for human consumption, including in the dry period.


Side effects
Hyper acute anaphylactic reactions in cattle.
Hypersensitivity reactions.
Overdoses can cause reduced visibility or blindness, anorexia, lack of coordination
and general weakness.


Dosage:
For subcutaneous administration:
Sheep, cattle less than 200 kg : 1 ml per 10 kg body weight
Cattle over 200 kg : 20 ml plus 5 ml per 100 kg of extra body weight
Do not administer more than 20 ml in cattle per injection site.


Withdrawal times:
For meat: 50 days.


Packaging: 50ml 100 ml.


Shelf Life: 2 years